In London on Monday the FTSE 100 fell 1.05 percent to 6,459.3 and the FTSE 250 dropped 1.07 percent to 11,177.9.
The biggest loser on the 100 was British Energy Group (LSE: BGY), which fell 8.12 percent to 532p on the news that two nuclear generators will be out of service longer than previously anticipated after new problems there.
Banks were lower.
Lloyds TSB (LSE: LLOY) was 1.2 percent lower to 530p, while Barclays Bank (LSE: BARC; NYSE: BCS; TYO: 8642) was down 1.6 percent to 580p and Royal Bank of Scotland (LSE: RBS; NYSE: RBS PRM) dropped 1.7 percent to 502p.
Miners fell after base metals prices dropped.
BHP Billiton (LSE: BLT; ASX: BHP; NYSE: BHP) was down 3.9 percent to £17.64 and Vedanta Resources (LSE: VED) was 5.04 percent lower to £20.54, while Xstrata (LSE: XTA) also fell 5.04 percent to £36.20 and Kazakhmys (LSE: KAZ) dropped 5.15 percent to €14.55.
With crude oil prices also lower, Tullow Oil was down 5.79 percent to 585.5p.
Among gainers on the day, supermarket chain Wm Morrison (LSE: MRW) was up 1.62 percent to 297.25p while elsewhere in the retail sector Home Retail (LSE: HOME) added 1.81 percent to 380p.
Cruise line operator Carnival (LSE: CCL; NYSE: CCL) gained 1.61 percent to £22.68.